Nanotechnology and Biomedicine(6)
Source: Neelina H. Malsch_Biomedical Nanotechnology
Del Campo and Bruce review the potential of nanotechnology for high throughput screening. The complexity and diversity of biomolecules and the range of external agents affecting biomolecules underline the importance of this capability. The current approaches and future trends are outlined for various groups of diseases, tissue lapping, and therapeutics. The most successful methods are based on flat surface and fiberoptic microarrays, microfluidics, and quantum dots.Nanoscale sensors and their integration into biological and chemical detection devices for defense purposes are reviewed by Shipbaugh et al.Typical threats and solutions for measuring, networking, and transmitting information are presented. Airborne and contact exposures can be evaluated using nanoscale princi- ples of operation for sensing. Key challenges for future research for biological and chemical detection are outlined.One example of the complexity of the scientific issues identified at the interface between synthetic and biological materials and systems is the study of toxicity caused by dendrimers. Generation dendrimers of particular diameters and electrically and positively charged can actually rip lipid bilayers from cells to form micellar- like structures, leading to cytotoxicity. The health concerns caused by nanotechnology products must receive full consideration from the private sector and government organizations because of the specific properties and types of complex interactions at the nanoscale.
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